Efficient parallel synthesis of macrocyclic peptidomimetics.
Bioorg Med Chem Lett
; 18(16): 4731-5, 2008 Aug 15.
Article
en En
| MEDLINE
| ID: mdl-18640834
ABSTRACT
A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studies on the macrocyclization step are reported.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Péptidos Cíclicos
/
Química Farmacéutica
Idioma:
En
Revista:
Bioorg Med Chem Lett
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2008
Tipo del documento:
Article