Insight in ALS: awareness of behavioral change in patients with and without FTD.
Amyotroph Lateral Scler
; 11(1-2): 52-6, 2010.
Article
en En
| MEDLINE
| ID: mdl-19714539
ABSTRACT
UNLABELLED Although impaired insight is a core diagnostic criterion for establishing the diagnosis of frontotemporal dementia (FTD), insight has rarely been studied in amyotrophic lateral sclerosis (ALS). OBJECTIVE:
To determine differences between patient and informant (caregiver) reports of behavior and behavioral change in amyotrophic lateral sclerosis.METHODS:
Behavioral data for 17 patients with ALS and 4 patients with ALS-FTD were analyzed. Behavioral changes were evaluated using the Frontal Systems Behavior Scale (FrSBe). We compared premorbid to current behavioral profiles and patient self-reports with those of their informants to determine the level of awareness regarding behavioral changes since the onset of ALS.RESULTS:
ALS patients without FTD had normal insight, as defined by this study, although self-reports suggested mild behavioral abnormalities. In contrast, patients with ALS-FTD revealed a marked loss of insight regarding profound changes in behavior.CONCLUSIONS:
Patients with ALS-FTD exhibit a profound lack of insight, which is not found in non-demented ALS patients. Patients without dementia have normal insight, although they report mild behavioral changes that might reflect a psychological response to the disease.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Conducta Social
/
Demencia Frontotemporal
/
Esclerosis Amiotrófica Lateral
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Amyotroph Lateral Scler
Asunto de la revista:
NEUROLOGIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos