Aspirin for lower limb arthroplasty thromboprophylaxis: review of international guidelines.
Ir J Med Sci
; 180(3): 627-32, 2011 Sep.
Article
en En
| MEDLINE
| ID: mdl-21286842
ABSTRACT
INTRODUCTION:
Aspirin is one of the pharmacological agents used for thromboprophylaxis. MATERIALS ANDMETHODS:
National thromboprophylaxis guidelines, peer-reviewed studies and data from national joint register of England and Wales were analysed for evidence regarding the efficacy of aspirin versus other agents in thromboprophylaxis and the recommendations of guidelines.RESULTS:
Two of five guidelines reviewed recommend the use of aspirin for thromboprophylaxis. Aspirin is used as thromboprophylactic agent in approximately 25% of patients undergoing total hip and total knee arthroplasty in year 2006 in England and Wales. There is no difference in mortality in these patients compared to patients on other pharmacological agents.CONCLUSION:
There is conflicting evidence and differences in interpretation of the data from the literature. If specific outcome measures and complications such as symptomatic DVT, PE and bleeding were logged in arthroplasty registers, the resulting data would be useful in individualised decision-making.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Embolia Pulmonar
/
Aspirina
/
Artroplastia de Reemplazo de Cadera
/
Artroplastia de Reemplazo de Rodilla
/
Trombosis de la Vena
/
Anticoagulantes
Tipo de estudio:
Guideline
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Ir J Med Sci
Año:
2011
Tipo del documento:
Article
País de afiliación:
Irlanda