Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.

Sun, Qian; Chen, Xinxin; Ma, Jianhui; Peng, Haiyong; Wang, Fang; Zha, Xiaojun; Wang, Yanan; Jing, Yanling; Yang, Hongwang; Chen, Rongrong; Chang, Long; Zhang, Yu; Goto, June; Onda, Hiroaki; Chen, Tong; Wang, Ming-Rong; Lu, Youyong; You, Han; Kwiatkowski, David; Zhang, Hongbing

Sun, Qian; Chen, Xinxin; Ma, Jianhui; Peng, Haiyong; Wang, Fang; Zha, Xiaojun; Wang, Yanan; Jing, Yanling; Yang, Hongwang; Chen, Rongrong; Chang, Long; Zhang, Yu; Goto, June; Onda, Hiroaki; Chen, Tong; Wang, Ming-Rong; Lu, Youyong; You, Han; Kwiatkowski, David; Zhang, Hongbing.

Afiliación

Sun Q; State Key Laboratory of Medical Molecular Biology, Department of Physiology and Pathophysiology, Institute of Basic Medical Sciences and School of Basic Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100005, China.

Proc Natl Acad Sci U S A ; 108(10): 4129-34, 2011 Mar 08.

Article en En | MEDLINE | ID: mdl-21325052

Asunto(s)

Neoplasias/patología; Piruvato Quinasa/metabolismo; Serina-Treonina Quinasas TOR/fisiología; Aerobiosis; Animales; Proliferación Celular; Genes myc; Glucólisis; Humanos; Ratones; Neoplasias/enzimología; Neoplasias/metabolismo; Serina-Treonina Quinasas TOR/metabolismo; Regulación hacia Arriba

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piruvato Quinasa / Serina-Treonina Quinasas TOR / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2011 Tipo del documento: Article País de afiliación: China

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