Identification and susceptibility of Rhizomucor spp. isolated from patients with cutaneous zygomycosis in China.
Med Mycol
; 49(8): 799-805, 2011 Nov.
Article
en En
| MEDLINE
| ID: mdl-21449693
ABSTRACT
Zygomycosis is a relatively uncommon mycosis with a morbidity that is increasing worldwide. Cutaneous zygomycosis, one of the clinical manifestations of the disease, has also emerged in recent decades. The major reported etiologic agents in China include Rhizomucor spp., Rhizopus spp., Mucor spp., and Lichtheimia spp. (formerly Absidia spp.). This study examined 11 clinical isolates of Rhizomucor that belong to three species (R. variabilis, R. regularior, and R. chlamydosporus). They were identified by both morphological and molecular methods and were found to have a high degree of correlation. In vitro susceptibility of the Rhizomucor isolates to seven antifungal drugs (amphotericin B, itraconazole, terbinafine, voriconazole, fluconazole, flucytosine, and micafungin) were tested, which resulted in amphotericin B being found to be the most active agent against all species evaluated in this study. The investigation also reviewed case reports of cutaneous zygomycosis in China.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Anfotericina B
/
Rhizomucor
/
Dermatomicosis
/
Mucormicosis
/
Antifúngicos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Med Mycol
Asunto de la revista:
MEDICINA VETERINARIA
/
MICROBIOLOGIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
China