Assessment of pituitary adenoma volumetric change using longitudinal MR image registration.
Neuroradiology
; 54(5): 435-43, 2012 May.
Article
en En
| MEDLINE
| ID: mdl-21647587
ABSTRACT
INTRODUCTION:
Change detection is a crucial factor in monitoring of slowly evolving pathologies. The objective of the study was to test a semi-automatic method applied on longitudinal MRI monitoring of volume change in pituitary macroadenomas.METHODS:
The proposed method is based on a visual comparison of geometrically corrected, co-registered, intensity-normalized contrast-enhanced (CE) 3D GRE T1-weighted images. Qualitative volume changes based on this applied method were compared with experts' readings of conventional pre- and post-CE 2D T1-weighted images. Magnetic resonance (MR) imaging was performed two to four times in 13 patients with a total combination of 29 time points.RESULTS:
Compared to conventional 2D MR readings, a diagnosis of tumor growth (yes/no) was changed in 5 of 13 patients (38%) at 9 of the 29 combinations of time points (31%) using the 3D-based semi-automatic method. With manual tumor tracings as reference, McNemar's test showed a significant difference between the two methods.CONCLUSION:
Visual comparison of geometrically corrected, intensity-normalized, and affine-aligned longitudinal 3D images may enable more accurate assessment of qualitative volumetric change in pituitary adenomas than conventional reading of 2D images.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Hipofisarias
/
Imagen por Resonancia Magnética
/
Adenoma
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neuroradiology
Año:
2012
Tipo del documento:
Article
País de afiliación:
Noruega