[A national online survey applied to patients with celiac disease in Chile]. / Encuesta nacional online aplicada en pacientes con enfermedad celíaca en Chile.
Rev Med Chil
; 139(7): 841-7, 2011 Jul.
Article
en Es
| MEDLINE
| ID: mdl-22051820
ABSTRACT
BACKGROUND:
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Its prevalence in Europe and the USA is 0.5 to 1%.AIM:
To analyze epidemiological aspects and degree of compliance with gluten-free diet (GFD) among Chilean individuals with CD. MATERIAL ANDMETHODS:
Subjects with confirmed or suspected CD were invited to answer an online survey published on the web at www.fundacionconvivir.cl. The answers were reinforced with a telephone interview.RESULTS:
The survey was answered by 1212 subjects (79% females). Median age at diagnosis was 25.8 years (range 1 to 84 years), with a bimodal curve with two peaks at less than 3 years and at 20 to 40 years of age. The diagnosis was made only by serologic markers in 9%, only by intestinal biopsy in 17.5%, and by a combination of both methods in 70%o. Conditions associated with CD were reported by 30% > of subjects and 20% > had relatives with CD. The GFD was strictly adhered to by 70% >, occasionally by 27% > and never by 3% >. Seventy five percent of subjects with a strict adherence to GFD had a favorable clinical response compared with 42% > of those with incomplete or lack of adherence (odds ratio 4.0, 95% > confidence intervals 2.8-5.7p < 0.01).CONCLUSIONS:
In 30% of respondents, the diagnosis of CD was not confirmed according to international guidelines that require serology and duodenal biopsy. One third of subjects recognized a poor compliance with GFD. Those with a strict adherence to it had a more favorable clinical course. However, 25% > did not experience a clinical improvement despite a strict GFD, a finding which requires further study.
Texto completo:
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Bases de datos:
MEDLINE
Asunto principal:
Enfermedad Celíaca
/
Cooperación del Paciente
/
Dieta Sin Gluten
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
Límite:
Adolescent
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Adult
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Aged
/
Aged80
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Child
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Child, preschool
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Female
/
Humans
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Infant
/
Male
País/Región como asunto:
America do sul
/
Chile
Idioma:
Es
Revista:
Rev Med Chil
Año:
2011
Tipo del documento:
Article
País de afiliación:
Chile