Stepwise sequential aneuploidy screening in clinical practice.
J Clin Ultrasound
; 40(1): 26-30, 2012 Jan.
Article
en En
| MEDLINE
| ID: mdl-22102396
ABSTRACT
PURPOSE:
To evaluate stepwise sequential screening (SSS) efficiency in clinical practice.METHODS:
All singletons undergoing SSS in a single practice by NTQR (Nuchal Translucency Quality Review Program)-credentialed providers in a 2-year period were included. Prenatal diagnosis was offered to all screen-positive women and those with a nuchal translucency ≥3.5 mm or cystic hygroma at the 11- to 14-week scan. Data were extracted from prospectively ascertained serum screening and genetics databases.RESULTS:
A total of 2,726 patients were screened, with SSS detecting all eight cases of trisomy 21 and all seven cases of other aneuploidies at a 4.3% screen-positive rate.CONCLUSIONS:
Stepwise sequential screening offers excellent aneuploidy screening efficiency when introduced into clinical practice.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Diagnóstico Prenatal
/
Algoritmos
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Trastornos de los Cromosomas
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Aneuploidia
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
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Observational_studies
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Screening_studies
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
J Clin Ultrasound
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos