Relationship between anxiety disorders and depressive disorders in patients with cerebrovascular injury.
Arch Gen Psychiatry
; 47(3): 246-51, 1990 Mar.
Article
en En
| MEDLINE
| ID: mdl-2306166
ABSTRACT
The interaction between anxiety disorder and major depressive disorder in patients with cerebrovascular lesions was examined in a controlled, 2 x 2 study design. A consecutive series of 24 patients who met criteria for major depression only were compared with 6 patients who met criteria for both major depression and generalized anxiety disorder, and 45 patients who did not meet criteria for either major depression of generalized anxiety. Among patients with positive computed tomographic scans, the anxious-depressed group (n = 19) showed a significantly higher frequency of cortical lesions, while patients with major depression only (n = 15) had a significantly higher frequency of subcortical (basal ganglia) strokes. No significant between-group differences were found in other variables, such as demographic variables, familial and personal history of psychiatric disorders, and neurologic deficits. These findings suggest that, in this mostly black, low-socioeconomic-status population, cortical vs subcortical lesion location may play an important role in determining whether severe anxiety occurs in patients with post-stroke major depression.
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Bases de datos:
MEDLINE
Asunto principal:
Trastornos de Ansiedad
/
Trastornos Cerebrovasculares
/
Trastorno Depresivo
Tipo de estudio:
Etiology_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Gen Psychiatry
Año:
1990
Tipo del documento:
Article
País de afiliación:
Moldova