The characteristics of purified HL60 tuftsin receptors.
Mol Cell Biochem
; 92(1): 77-84, 1990 Jan 18.
Article
en En
| MEDLINE
| ID: mdl-2308578
ABSTRACT
The purification and characteristics of purified HL60 tuftsin receptors are described. Purification was accomplished by affinity chromatography similar to that described earlier, wherein a tuftsin analog Thr-Lys-Pro-Pro-Arg, is covalently linked at the N alpha group to a solid support. The receptor consists presumably of two subunits approximately 66 KDa and 57 KDa. The dissociation constant of the receptor complex is 4.7 X 10(-8) M with 5 X 10(4) receptors per cell. It can form oligomers with an Mr of about 560 KDa suggesting an octomeric structure, assuming the same number of each subunit is associated.
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Bases de datos:
MEDLINE
Asunto principal:
Tuftsina
/
Receptores Inmunológicos
Límite:
Humans
Idioma:
En
Revista:
Mol Cell Biochem
Año:
1990
Tipo del documento:
Article