Surgical margins in head and neck squamous cell carcinoma: what is 'close'?
Eur Arch Otorhinolaryngol
; 270(10): 2603-9, 2013 Sep.
Article
en En
| MEDLINE
| ID: mdl-23271033
ABSTRACT
The aim of this systematic review is to evaluate the definition of close margin in head and neck squamous cell carcinoma (HNSCC), and its possible prognostic significance. An appropriate string was run on PubMed to retrieve articles discussing the 'close' surgical margin issue in HNSCC. A double cross-check was performed on citations and full-text articles retrieved. In total, 348 articles were identified. Further references were included by using the option "Titles in your search terms" option in PubMed. 15 papers were finally included for qualitative synthesis. In vocal cord surgery of HNSCC, a close margin could be considered to be ≤1 mm, in the larynx ≤5 mm, in the oral cavity ≤4 mm, and in the oropharynx ≤5 mm. In each patient, the choice of extent of close margin should be balanced against general condition, tumor stage, and functional issues to indicate appropriate adjuvant therapy.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias de la Boca
/
Carcinoma de Células Escamosas
/
Neoplasias Orofaríngeas
/
Neoplasias Laríngeas
/
Neoplasias de Cabeza y Cuello
/
Recurrencia Local de Neoplasia
Tipo de estudio:
Prognostic_studies
/
Qualitative_research
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Eur Arch Otorhinolaryngol
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Italia