A new HA/TTCP material for bone augmentation: an in vivo histological pilot study in primates sinus grafting.
Implant Dent
; 22(1): 83-90, 2013 Feb.
Article
en En
| MEDLINE
| ID: mdl-23296033
ABSTRACT
OBJECTIVE:
Synthetic calcium phosphate bone substitutes are widely used in sinus graft procedures due to their osteoconductive and biocompatible properties. Hydroxyapatite (HA), beta-tricalcium phosphate (ß-TCP), and HA/ß-TCP composite are the most applied materials. The aim of this study was to propose a new mineralogical formulation, HA/tetracalcium phosphate (TTCP), as biomaterial for bone regeneration in the maxillary sinus.METHODS:
Sinus grafts were performed by using granules of a HA/TTCP blend and a collagen membrane. Bone response at time points of 14 and 17 weeks was histologically evaluated.RESULTS:
After 14 weeks of healing, histomorphometric analysis showed the formation of new bone trabeculae among HA/TTCP granules. After 17 weeks, the bone trabeculae were thicker and HA/TTCP granules were still present. Histomorphometric analysis revealed a bone graft contact (BGC) of 64%.CONCLUSIONS:
After 17 weeks from implantation, HA/TTCP synthetic bone graft performed very well as osteoconductivematerial:
BGC was found very high, and bone volume and vital bone showed an ideal bone density for implant placement. HA/TTCP granules are accounted for to accelerate new bone formation and to reduce the time needed for the graft healing, thus achieving high quantity of the new bone formed.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Fosfatos de Calcio
/
Durapatita
/
Sustitutos de Huesos
/
Elevación del Piso del Seno Maxilar
Límite:
Animals
Idioma:
En
Revista:
Implant Dent
Asunto de la revista:
ODONTOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Italia