Photodynamic detection and management of intraperitoneal spreading of primary peritoneal papillary serous carcinoma in a man: report of a case.
Surg Today
; 44(2): 373-7, 2014 Feb.
Article
en En
| MEDLINE
| ID: mdl-23435809
ABSTRACT
As a peritoneal surface malignancy, primary peritoneal papillary serous carcinoma (PPPSC) almost always occurs in women. Our search of the literature found only two previous case reports of men with PPPSC, both with very short survival. We report the case of a 63-year-old man with PPPSC, treated effectively with cytoreductive surgery and docetaxel-based hyperthermic intraperitoneal chemotherapy following six cycles of docetaxel-based laparoscopic neoadjuvant intraperitoneal and cisplatin-based systemic chemotherapy. Furthermore, we detected intraoperative intraperitoneal spreading of the tumor after the oral administration of 5-amino levulinic acid (5-ALA). The patient remains in good health without ascites 18 months after his diagnosis. Thus, primary peritoneal papillary serous carcinoma should be managed by intraperitoneal chemotherapy combined with peritonectomy procedures. Moreover, the intraoperative detection of the intraperitoneal spreading of the tumor after administering oral 5-ALA shows that this is an exciting and promising diagnostic technique, which needs to be confirmed by further studies.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Peritoneales
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Peritoneo
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Fármacos Fotosensibilizantes
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Cistadenocarcinoma Seroso
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Cistadenocarcinoma Papilar
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Ácido Aminolevulínico
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Surg Today
Año:
2014
Tipo del documento:
Article