Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.
Pharmacol Res
; 76: 132-48, 2013 Oct.
Article
en En
| MEDLINE
| ID: mdl-23942037
Palabras clave
2,2-dihydroxychalcone; ALAS 1; ARE; BV2 microglia; BVR; CA; CAA; CO-RMs; CoPP; DHC; DMF; H; HF-E2 p45-related factor 2; HO-1; Heme metabolism; INF-γ; ISL; Inflammation; Keap-1; Kelch-like ECH-associated protein-1; LPS; Nrf2; PGE2; S; SC; Small molecule activators; SnPPIX; TNF-α; antioxidant responsive element; biliverdin reductase; carbon monoxide-releasing molecules; carnosic acid; carnosol; cobalt protoporphyrin IX; delta-aminolevulinate synthase 1; dimethyl fumarate; heme oxygenase-1; hemin; interferon-γ; isoliquiritigenin; lipopolysaccharide; prostglandin E2; shRNA; small hairpin RNA; sulforaphane; supercurcumin; tBH; tert-butyl hydroquinone; tin protoporphyrin IX; tumor necrosis factor alpha
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Microglía
/
Hemo-Oxigenasa 1
/
Factor 2 Relacionado con NF-E2
/
Bibliotecas de Moléculas Pequeñas
/
Hemo
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Pharmacol Res
Asunto de la revista:
FARMACOLOGIA
Año:
2013
Tipo del documento:
Article