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Influence of exposure to tobacco cigarette smoke on the eosinophil count in the nasal mucosa of young patients with perennial allergic rhinitis.
Montano-Velazquez, B B; Garcia Vazquez, F J; Navarrete, R C; Martinez, M D M; Gonzalez, L F; Jauregui-Renaud, K.
Afiliación
  • Montano-Velazquez BB; Unidad de Investigacion Medica en Otoneurologia, Instituto Mexicano del Seguro Social, Mexico.
Rhinology ; 51(3): 253-8, 2013 Sep.
Article en En | MEDLINE | ID: mdl-23943733
ABSTRACT

BACKGROUND:

To assess the influence of exposure to tobacco cigarette smoke on the eosinophil count and the frequency of apoptosis of eosinophils in the nasal mucosa of teenagers with perennial allergic rhinitis.

METHODS:

Fifty patients were evaluated (aged 10 to 19 years old) 25 patients with and 25 patients with no recent exposure to tobacco cigarette smoke, by means of The Global Youth Tobacco Survey and cotinine/creatinine ratio. After a clinical evaluation, all the patients replied to a validated questionnaire of the severity of nasal symptoms; then, a nasal sample was processed to identify the eosinophil count and the frequency of apoptosis of eosinophils.

RESULTS:

Patients with active exposure to tobacco cigarette smoke had higher eosinophil counts than patients with no exposure to the smoke. In the two groups, apoptosis of eosinophils in the nasal mucosa was scarce and no significant correlation was observed between the frequency/severity of the nasal symptoms and the eosinophil count.

CONCLUSION:

Teenagers with perennial allergic rhinitis and active exposure to tobacco cigarette smoke may show increased eosinophil counts in the nasal mucosa, which might not be related to apoptosis of eosinophils or to the frequency/severity of nasal symptoms.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Contaminación por Humo de Tabaco / Rinitis Alérgica Perenne / Eosinófilos / Mucosa Nasal Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Rhinology Año: 2013 Tipo del documento: Article País de afiliación: México

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Contaminación por Humo de Tabaco / Rinitis Alérgica Perenne / Eosinófilos / Mucosa Nasal Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Rhinology Año: 2013 Tipo del documento: Article País de afiliación: México