Diterpenoids and sesquiterpenoids from the roots of Illicium majus.
J Nat Prod
; 76(10): 1976-83, 2013 Oct 25.
Article
en En
| MEDLINE
| ID: mdl-24070022
ABSTRACT
Five new diterpenoids (1-5), five new sesquiterpenoids (6-10), and three known compounds (11-13) were isolated from the roots of Illicium majus. Their structures were elucidated by extensive spectroscopic analysis. The absolute configuration of 1 was assigned by X-ray crystallography, whereas those of the 1,2-diol moieties in 3 and 4 were determined using Snatzke's method. The abietane acids 1, 2, 11, 12, and 13 displayed antiviral activity against the Coxsackie B3 virus, with IC50 values of 3.3-51.7 µM/mL.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Antivirales
/
Sesquiterpenos
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Medicamentos Herbarios Chinos
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Illicium
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Abietanos
Idioma:
En
Revista:
J Nat Prod
Año:
2013
Tipo del documento:
Article