Hypoxia signaling--license to metastasize.
Cancer Discov
; 3(10): 1103-4, 2013 Oct.
Article
en En
| MEDLINE
| ID: mdl-24124230
ABSTRACT
Hypoxia-inducible factors (HIF) have long been linked to malignant tumor phenotypes in various cancer types, and several downstream mediators of HIF action are deregulated in metastatic carcinomas. A new study links hypoxia-induced collagen remodeling to sarcoma progression, providing evidence for unifying mechanisms of carcinoma and sarcoma metastasis.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Sarcoma
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Hipoxia de la Célula
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Colágeno
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Procolágeno-Lisina 2-Oxoglutarato 5-Dioxigenasa
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Subunidad alfa del Factor 1 Inducible por Hipoxia
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Minoxidil
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Metástasis de la Neoplasia
Límite:
Animals
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Humans
Idioma:
En
Revista:
Cancer Discov
Año:
2013
Tipo del documento:
Article