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NVP-BEZ235, a dual PI3K/mTOR inhibitor, inhibits osteosarcoma cell proliferation and tumor development in vivo with an improved survival rate.
Gobin, Bérengère; Battaglia, Séverine; Lanel, Rachel; Chesneau, Julie; Amiaud, Jérôme; Rédini, Françoise; Ory, Benjamin; Heymann, Dominique.
Afiliación
  • Gobin B; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Battaglia S; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Lanel R; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Chesneau J; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Amiaud J; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Rédini F; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France; Nanrtes University Hospital, rue Gaston Veil, 44035, Nantes, France.
  • Ory B; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France.
  • Heymann D; INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes 44035, France; Université de Nantes, Nantes atlantique universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumors, Nantes, France; Nanrtes University Hospital, rue Gaston Veil, 44035, Nantes, France. Electr
Cancer Lett ; 344(2): 291-8, 2014 Mar 28.
Article en En | MEDLINE | ID: mdl-24333720
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / Neoplasias Óseas / Osteosarcoma / Serina-Treonina Quinasas TOR / Inhibidores de las Quinasa Fosfoinosítidos-3 / Imidazoles / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Animals / Humans / Male Idioma: En Revista: Cancer Lett Año: 2014 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / Neoplasias Óseas / Osteosarcoma / Serina-Treonina Quinasas TOR / Inhibidores de las Quinasa Fosfoinosítidos-3 / Imidazoles / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Animals / Humans / Male Idioma: En Revista: Cancer Lett Año: 2014 Tipo del documento: Article País de afiliación: Francia