Structural plasticity within the barrel cortex during initial phases of whisker-dependent learning.
J Neurosci
; 34(17): 6078-83, 2014 Apr 23.
Article
en En
| MEDLINE
| ID: mdl-24760867
ABSTRACT
We report learning-related structural plasticity in layer 1 branches of pyramidal neurons in the barrel cortex, a known site of sensorimotor integration. In mice learning an active, whisker-dependent object localization task, layer 2/3 neurons showed enhanced spine growth during initial skill acquisition that both preceded and predicted expert performance. Preexisting spines were stabilized and new persistent spines were formed. These findings suggest rapid changes in connectivity between motor centers and sensory cortex guide subsequent sensorimotor learning.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Corteza Somatosensorial
/
Vibrisas
/
Aprendizaje
/
Plasticidad Neuronal
/
Neuronas
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
J Neurosci
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido