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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Madiraju, Anila K; Erion, Derek M; Rahimi, Yasmeen; Zhang, Xian-Man; Braddock, Demetrios T; Albright, Ronald A; Prigaro, Brett J; Wood, John L; Bhanot, Sanjay; MacDonald, Michael J; Jurczak, Michael J; Camporez, Joao-Paulo; Lee, Hui-Young; Cline, Gary W; Samuel, Varman T; Kibbey, Richard G; Shulman, Gerald I.
Afiliación
  • Madiraju AK; 1] Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA [3] Howard Hughes Medical Institute, Yale University School of Medici
  • Erion DM; 1] Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA [3] Howard Hughes Medical Institute, Yale University School of Medici
  • Rahimi Y; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Zhang XM; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Braddock DT; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Albright RA; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Prigaro BJ; Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
  • Wood JL; Cancer Prevention Research Institute of Texas Scholar, Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, USA.
  • Bhanot S; Isis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, USA.
  • MacDonald MJ; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA, 53706.
  • Jurczak MJ; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Camporez JP; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Lee HY; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Cline GW; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Samuel VT; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Kibbey RG; 1] Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
  • Shulman GI; 1] Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA [3] Howard Hughes Medical Institute, Yale University School of Medici
Nature ; 510(7506): 542-6, 2014 Jun 26.
Article en En | MEDLINE | ID: mdl-24847880
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gluconeogénesis / Glicerolfosfato Deshidrogenasa / Metformina / Mitocondrias Límite: Animals / Humans / Male Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Gluconeogénesis / Glicerolfosfato Deshidrogenasa / Metformina / Mitocondrias Límite: Animals / Humans / Male Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article