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The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.
De Houwer, Stéphanie; Demeulemeester, Jonas; Thys, Wannes; Rocha, Susana; Dirix, Lieve; Gijsbers, Rik; Christ, Frauke; Debyser, Zeger.
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  • De Houwer S; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Demeulemeester J; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Thys W; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Rocha S; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Dirix L; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Gijsbers R; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Christ F; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.
  • Debyser Z; From the Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, 3000, Leuven, Belgium zeger.debyser@med.kuleuven.be.
J Biol Chem ; 289(36): 25351-61, 2014 Sep 05.
Article en En | MEDLINE | ID: mdl-25063804
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: VIH-1 / Integrasa de VIH / Beta Carioferinas / Mutación Límite: Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: VIH-1 / Integrasa de VIH / Beta Carioferinas / Mutación Límite: Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Bélgica