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Ancient human genomes suggest three ancestral populations for present-day Europeans.
Lazaridis, Iosif; Patterson, Nick; Mittnik, Alissa; Renaud, Gabriel; Mallick, Swapan; Kirsanow, Karola; Sudmant, Peter H; Schraiber, Joshua G; Castellano, Sergi; Lipson, Mark; Berger, Bonnie; Economou, Christos; Bollongino, Ruth; Fu, Qiaomei; Bos, Kirsten I; Nordenfelt, Susanne; Li, Heng; de Filippo, Cesare; Prüfer, Kay; Sawyer, Susanna; Posth, Cosimo; Haak, Wolfgang; Hallgren, Fredrik; Fornander, Elin; Rohland, Nadin; Delsate, Dominique; Francken, Michael; Guinet, Jean-Michel; Wahl, Joachim; Ayodo, George; Babiker, Hamza A; Bailliet, Graciela; Balanovska, Elena; Balanovsky, Oleg; Barrantes, Ramiro; Bedoya, Gabriel; Ben-Ami, Haim; Bene, Judit; Berrada, Fouad; Bravi, Claudio M; Brisighelli, Francesca; Busby, George B J; Cali, Francesco; Churnosov, Mikhail; Cole, David E C; Corach, Daniel; Damba, Larissa; van Driem, George; Dryomov, Stanislav; Dugoujon, Jean-Michel.
Afiliación
  • Lazaridis I; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Patterson N; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Mittnik A; Institute for Archaeological Sciences, University of Tübingen, Tübingen 72074, Germany.
  • Renaud G; Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Mallick S; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Kirsanow K; Institute of Anthropology, Johannes Gutenberg University Mainz, Mainz D-55128, Germany.
  • Sudmant PH; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.
  • Schraiber JG; 1] Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA. [2] Department of Integrative Biology, University of California, Berkeley, California 94720-3140, USA.
  • Castellano S; Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Lipson M; Department of Mathematics and Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Berger B; 1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA. [2] Department of Mathematics and Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
  • Economou C; Archaeological Research Laboratory, Stockholm University, 114 18, Sweden.
  • Bollongino R; Institute of Anthropology, Johannes Gutenberg University Mainz, Mainz D-55128, Germany.
  • Fu Q; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany. [3] Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, IVPP, CAS, Beijing 100049, China.
  • Bos KI; Institute for Archaeological Sciences, University of Tübingen, Tübingen 72074, Germany.
  • Nordenfelt S; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Li H; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • de Filippo C; Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Prüfer K; Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Sawyer S; Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany.
  • Posth C; Institute for Archaeological Sciences, University of Tübingen, Tübingen 72074, Germany.
  • Haak W; Australian Centre for Ancient DNA and Environment Institute, School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5005, Australia.
  • Hallgren F; The Cultural Heritage Foundation, Västerås 722 12, Sweden.
  • Fornander E; The Cultural Heritage Foundation, Västerås 722 12, Sweden.
  • Rohland N; 1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
  • Delsate D; 1] National Museum of Natural History, L-2160, Luxembourg. [2] National Center of Archaeological Research, National Museum of History and Art, L-2345, Luxembourg.
  • Francken M; Department of Paleoanthropology, Senckenberg Center for Human Evolution and Paleoenvironment, University of Tübingen, Tübingen D-72070, Germany.
  • Guinet JM; National Museum of Natural History, L-2160, Luxembourg.
  • Wahl J; State Office for Cultural Heritage Management Baden-Württemberg, Osteology, Konstanz D-78467, Germany.
  • Ayodo G; Center for Global Health and Child Development, Kisumu 40100, Kenya.
  • Babiker HA; 1] Institutes of Evolution, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK. [2] Biochemistry Department, Faculty of Medicine, Sultan Qaboos University, Alkhod, Muscat 123, Oman.
  • Bailliet G; Laboratorio de Genética Molecular Poblacional, Instituto Multidisciplinario de Biología Celular (IMBICE), CCT-CONICET &CICPBA, La Plata, B1906APO, Argentina.
  • Balanovska E; Research Centre for Medical Genetics, Moscow 115478, Russia.
  • Balanovsky O; 1] Research Centre for Medical Genetics, Moscow 115478, Russia. [2] Vavilov Institute for General Genetics, Moscow 119991, Russia.
  • Barrantes R; Escuela de Biología, Universidad de Costa Rica, San José 2060, Costa Rica.
  • Bedoya G; Institute of Biology, Research group GENMOL, Universidad de Antioquia, Medellín, Colombia.
  • Ben-Ami H; Rambam Health Care Campus, Haifa 31096, Israel.
  • Bene J; Department of Medical Genetics and Szentagothai Research Center, University of Pécs, Pécs H-7624, Hungary.
  • Berrada F; Al Akhawayn University in Ifrane (AUI), School of Science and Engineering, Ifrane 53000, Morocco.
  • Bravi CM; Laboratorio de Genética Molecular Poblacional, Instituto Multidisciplinario de Biología Celular (IMBICE), CCT-CONICET &CICPBA, La Plata, B1906APO, Argentina.
  • Brisighelli F; Forensic Genetics Laboratory, Institute of Legal Medicine, Università Cattolica del Sacro Cuore, Rome 00168, Italy.
  • Busby GB; 1] Department of Zoology, University of Oxford, Oxford OX1 3PS, UK. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Cali F; Laboratorio di Genetica Molecolare, IRCCS Associazione Oasi Maria SS, Troina 94018, Italy.
  • Churnosov M; Belgorod State University, Belgorod 308015, Russia.
  • Cole DE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 1L5, Canada.
  • Corach D; Servicio de Huellas Digitales Genéticas, School of Pharmacy and Biochemistry, Universidad de Buenos Aires, 1113 CABA, Argentina.
  • Damba L; Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia.
  • van Driem G; Institute of Linguistics, University of Bern, Bern CH-3012, Switzerland.
  • Dryomov S; Laboratory of Human Molecular Genetics, Institute of Molecular and Cellular Biology, Russian Academy of Science, Siberian Branch, Novosibirsk 630090, Russia.
  • Dugoujon JM; Anthropologie Moléculaire et Imagerie de Synthèse, CNRS UMR 5288, Université Paul Sabatier Toulouse III, Toulouse 31000, France.
Nature ; 513(7518): 409-13, 2014 Sep 18.
Article en En | MEDLINE | ID: mdl-25230663
ABSTRACT
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genoma Humano / Población Blanca Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: Asia / Europa Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genoma Humano / Población Blanca Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: Asia / Europa Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos