ALT telomeres borrow from meiosis to get moving.
Cell
; 159(1): 11-12, 2014 Sep 25.
Article
en En
| MEDLINE
| ID: mdl-25259914
ABSTRACT
Telomere clustering is required for the homologous recombination events that maintain chromosome ends in cells relying on alternative lengthening of telomeres (ALT). New data demonstrate that damage signaling at telomeres, a likely step in activating maintenance mechanisms, induces directional movement and synapsis driven by the machinery responsible for recombination in meiosis.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Recombinación Genética
/
Telómero
/
Emparejamiento Cromosómico
Límite:
Humans
Idioma:
En
Revista:
Cell
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos