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Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms.
Chen, Edwin; Schneider, Rebekka K; Breyfogle, Lawrence J; Rosen, Emily A; Poveromo, Luke; Elf, Shannon; Ko, Amy; Brumme, Kristina; Levine, Ross; Ebert, Benjamin L; Mullally, Ann.
Afiliación
  • Chen E; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Schneider RK; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Breyfogle LJ; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Rosen EA; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Poveromo L; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Elf S; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Ko A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Brumme K; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;
  • Levine R; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY; and.
  • Ebert BL; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Broad Institute, Cambridge, MA.
  • Mullally A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Broad Institute, Cambridge, MA.
Blood ; 125(2): 327-35, 2015 Jan 08.
Article en En | MEDLINE | ID: mdl-25281607

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Proteínas Proto-Oncogénicas / Proteínas de Unión al ADN / Janus Quinasa 2 / Trastornos Mieloproliferativos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Proteínas Proto-Oncogénicas / Proteínas de Unión al ADN / Janus Quinasa 2 / Trastornos Mieloproliferativos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article