The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients.

de Jonge, H; Elens, L; de Loor, H; van Schaik, R H; Kuypers, D R J

de Jonge, H; Elens, L; de Loor, H; van Schaik, R H; Kuypers, D R J.

Afiliación

de Jonge H; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.
Elens L; 1] Department of Clinical Chemistry, University Medical Center, Rotterdam, The Netherlands [2] Cliniques Universitaires Saint-Luc - UCL, Laboratory of Analytical Biochemistry & Louvain Centre for Toxicology and Applied Pharmacology (LTAP), Brussels, Belgium.
de Loor H; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.
van Schaik RH; Department of Clinical Chemistry, University Medical Center, Rotterdam, The Netherlands.
Kuypers DR; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.

Pharmacogenomics J ; 15(2): 144-52, 2015 Apr.

Article en En | MEDLINE | ID: mdl-25287072

Asunto(s)

Citocromo P-450 CYP3A/genética; Midazolam/farmacocinética; Polimorfismo de Nucleótido Simple/genética; Alelos; Estudios Transversales; Femenino; Genotipo; Humanos; Trasplante de Riñón; Masculino; Persona de Mediana Edad; Tacrolimus/farmacocinética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Midazolam / Polimorfismo de Nucleótido Simple / Citocromo P-450 CYP3A Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics J Asunto de la revista: BIOLOGIA MOLECULAR / FARMACOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Bélgica

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