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ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.
Peirs, Sofie; Matthijssens, Filip; Goossens, Steven; Van de Walle, Inge; Ruggero, Katia; de Bock, Charles E; Degryse, Sandrine; Canté-Barrett, Kirsten; Briot, Delphine; Clappier, Emmanuelle; Lammens, Tim; De Moerloose, Barbara; Benoit, Yves; Poppe, Bruce; Meijerink, Jules P; Cools, Jan; Soulier, Jean; Rabbitts, Terence H; Taghon, Tom; Speleman, Frank; Van Vlierberghe, Pieter.
Afiliación
  • Peirs S; Center for Medical Genetics.
  • Matthijssens F; Center for Medical Genetics.
  • Goossens S; Flanders Institute for Biotechnology Inflammation Research Center, and.
  • Van de Walle I; Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium;
  • Ruggero K; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, England, United Kingdom;
  • de Bock CE; Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, University of Leuven and Center for the Biology of Disease, Vlaams Instituut voor Biotechnologie, Leuven, Belgium;
  • Degryse S; Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, University of Leuven and Center for the Biology of Disease, Vlaams Instituut voor Biotechnologie, Leuven, Belgium;
  • Canté-Barrett K; Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Rotterdam, The Netherlands;
  • Briot D; Genome Rearrangements and Cancer Laboratory, U462 INSERM, Laboratoire Central d'Hématologie and Institut Universitaire d'Hématologie, Hopital Saint-Louis, Paris, France; and.
  • Clappier E; Genome Rearrangements and Cancer Laboratory, U462 INSERM, Laboratoire Central d'Hématologie and Institut Universitaire d'Hématologie, Hopital Saint-Louis, Paris, France; and.
  • Lammens T; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • De Moerloose B; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Benoit Y; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Poppe B; Center for Medical Genetics.
  • Meijerink JP; Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Rotterdam, The Netherlands;
  • Cools J; Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, University of Leuven and Center for the Biology of Disease, Vlaams Instituut voor Biotechnologie, Leuven, Belgium;
  • Soulier J; Genome Rearrangements and Cancer Laboratory, U462 INSERM, Laboratoire Central d'Hématologie and Institut Universitaire d'Hématologie, Hopital Saint-Louis, Paris, France; and.
  • Rabbitts TH; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, England, United Kingdom;
  • Taghon T; Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium;
  • Speleman F; Center for Medical Genetics.
  • Van Vlierberghe P; Center for Medical Genetics.
Blood ; 124(25): 3738-47, 2014 Dec 11.
Article en En | MEDLINE | ID: mdl-25301704
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfonamidas / Compuestos Bicíclicos Heterocíclicos con Puentes / Proteínas Proto-Oncogénicas c-bcl-2 / Ensayos Antitumor por Modelo de Xenoinjerto / Leucemia-Linfoma Linfoblástico de Células T Precursoras Límite: Animals / Child / Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfonamidas / Compuestos Bicíclicos Heterocíclicos con Puentes / Proteínas Proto-Oncogénicas c-bcl-2 / Ensayos Antitumor por Modelo de Xenoinjerto / Leucemia-Linfoma Linfoblástico de Células T Precursoras Límite: Animals / Child / Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article