Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
MAbs
; 7(1): 129-37, 2015.
Article
en En
| MEDLINE
| ID: mdl-25523454
Palabras clave
APC, antigen presenting cells; Antibody generation; CDR, complementarity determining region; CHO, Chinese hamster ovary; DMEM, dulbecco's modified eagles' medium; DTA, diphtheria toxin; ELISA, enzyme-linked immunosorbent assay; HLA, human leukocyte antigen; HTRF, homogenous time-resolved fluorescence; IL, interleukin; ILC2, type 2 innate lymphoid cells; IgG, immunoglobulin G; MHC, major histocompatibility complex; PADRE, pan HLA-DR-binding T cell epitope; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel; SLE, systemic lupus erythematosus; T-cell epitopes; TCR, T cell receptor; TT, tetanus tosxin; VH, variable region of immunoglobulin heavy chain; VL, variable region of immunoglobulin light chain; diphtheria toxin; hybridoma; immunological tolerance; mST2, mouse ST2; mouse ST2; tetanus toxin
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Receptores de Interleucina
/
Epítopos de Linfocito T
/
Anticuerpos Monoclonales de Origen Murino
/
Especificidad de Anticuerpos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Female
/
Humans
Idioma:
En
Revista:
MAbs
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Reino Unido