Abnormal Rho-associated kinase activity contributes to the dysfunctional myogenic response of cerebral arteries in type 2 diabetes.

Abd-Elrahman, Khaled S; Walsh, Michael P; Cole, William C

Abd-Elrahman, Khaled S; Walsh, Michael P; Cole, William C.

Afiliación

Abd-Elrahman KS; The Smooth Muscle Research Group, Libin Cardiovascular Institute, Hotchkiss Brain Institute, and the Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada.

Can J Physiol Pharmacol ; 93(3): 177-84, 2015 Mar.

Article en En | MEDLINE | ID: mdl-25660561

Asunto(s)

Arterias Cerebrales/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Miogenina/metabolismo; Quinasas Asociadas a rho/metabolismo; Animales; Circulación Cerebrovascular; Humanos

Palabras clave

Ca2+ sensitization; actin cytoskeleton; autorégulation cérébrale; cerebral autoregulation; cytosquelette d'actine; muscle lisse vasculaire; myosin light chain phosphatase; phosphatase de la chaine légère de la myosine; sensibilisation au Ca2+; vascular smooth muscle

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arterias Cerebrales / Miogenina / Diabetes Mellitus Tipo 2 / Quinasas Asociadas a rho Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Can J Physiol Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: Canadá

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