Detection of SMARCB1 loss in ascites cells in the diagnosis of an abdominal rhabdoid tumor.
Pediatr Blood Cancer
; 62(5): 897-900, 2015 May.
Article
en En
| MEDLINE
| ID: mdl-25663425
ABSTRACT
We report on how MLPA and Sequencing of SMARCB1/INI1/SNF5 might be applied for initial diagnosis of rhabdoid tumor patients. These techniques were successfully used to detect loss of SMARCB1 in tumor cells of the ascites in a 3-month-old patient in which tumor biopsy could not initially be made due to life threatening intraabdominal bleedings.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ascitis
/
Factores de Transcripción
/
Proteínas Cromosómicas no Histona
/
Biomarcadores de Tumor
/
Tumor Rabdoide
/
Proteínas de Unión al ADN
/
Neoplasias Abdominales
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Pediatr Blood Cancer
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Alemania