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Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1ß, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death.
Toki, Yusuke; Takenouchi, Takato; Harada, Hitoshi; Tanuma, Sei-ichi; Kitani, Hiroshi; Kojima, Shuji; Tsukimoto, Mitsutoshi.
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  • Toki Y; Department of Radiation Biosciences, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba, Japan; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510, Japan.
  • Takenouchi T; Animal Immune and Cell Biology Research Unit, Division of Animal Sciences, National Institute of Agrobiological Sciences, 1-2 Ohwashi, Tsukuba, Ibaraki 305-8634, Japan.
  • Harada H; Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3 Minamitamagaki-cho, Suzuka-shi, Mie, Japan.
  • Tanuma S; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510, Japan.
  • Kitani H; Animal Immune and Cell Biology Research Unit, Division of Animal Sciences, National Institute of Agrobiological Sciences, 1-2 Ohwashi, Tsukuba, Ibaraki 305-8634, Japan.
  • Kojima S; Department of Radiation Biosciences, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba, Japan.
  • Tsukimoto M; Department of Radiation Biosciences, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba, Japan. Electronic address: tsukim@rs.noda.tus.ac.jp.
Biochem Biophys Res Commun ; 458(4): 771-6, 2015 Mar 20.
Article en En | MEDLINE | ID: mdl-25681768
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Antígenos de Histocompatibilidad Clase I / Adenosina Trifosfato / Proteína HMGB1 / Interleucina-1beta / Receptores Purinérgicos P2X7 / Macrófagos del Hígado Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2015 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Antígenos de Histocompatibilidad Clase I / Adenosina Trifosfato / Proteína HMGB1 / Interleucina-1beta / Receptores Purinérgicos P2X7 / Macrófagos del Hígado Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2015 Tipo del documento: Article País de afiliación: Japón