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A novel technique for detecting antibiotic-resistant typhoid from rapid diagnostic tests.
Nic Fhogartaigh, Caoimhe; Dance, David A B; Davong, Viengmon; Tann, Pisey; Phetsouvanh, Rattanaphone; Turner, Paul; Dittrich, Sabine; Newton, Paul N.
Afiliación
  • Nic Fhogartaigh C; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Public Health England, London, England, United Kingdom.
  • Dance DA; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Public Health England, London, England, United Kingdom Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England.
  • Davong V; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR.
  • Tann P; Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
  • Phetsouvanh R; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR.
  • Turner P; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
  • Dittrich S; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England sabine@tropmedres.ac.
  • Newton PN; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England.
J Clin Microbiol ; 53(5): 1758-60, 2015 May.
Article en En | MEDLINE | ID: mdl-25762768
ABSTRACT
Fluoroquinolone-resistant typhoid is increasing. An antigen-detecting rapid diagnostic test (RDT) can rapidly diagnose typhoid from blood cultures. A simple, inexpensive molecular technique performed with DNA from positive RDTs accurately identified gyrA mutations consistent with phenotypic susceptibility testing results. Field diagnosis combined with centralized molecular resistance testing could improve typhoid management and surveillance in low-resource settings.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Salmonella typhi / Fiebre Tifoidea / Técnicas Bacteriológicas / Farmacorresistencia Bacteriana / Pruebas Diagnósticas de Rutina Tipo de estudio: Clinical_trials / Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Clin Microbiol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Salmonella typhi / Fiebre Tifoidea / Técnicas Bacteriológicas / Farmacorresistencia Bacteriana / Pruebas Diagnósticas de Rutina Tipo de estudio: Clinical_trials / Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Clin Microbiol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido