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Combat-Related Pythium aphanidermatum Invasive Wound Infection: Case Report and Discussion of Utility of Molecular Diagnostics.
Farmer, Aaron R; Murray, Clinton K; Driscoll, Ian R; Wickes, Brian L; Wiederhold, Nathan; Sutton, Deanna A; Sanders, Carmita; Mende, Katrin; Enniss, Brent; Feig, James; Ganesan, Anuradha; Rini, Elizabeth A; Vento, Todd J.
Afiliación
  • Farmer AR; San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA Aaron.r.farmer.mil@mail.mil.
  • Murray CK; San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA.
  • Driscoll IR; United States Army Institute of Surgical Research, JBSA Fort Sam Houston, Texas, USA.
  • Wickes BL; Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
  • Wiederhold N; Department of Pathology, Fungus Testing Laboratory University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
  • Sutton DA; Department of Pathology, Fungus Testing Laboratory University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
  • Sanders C; Department of Pathology, Fungus Testing Laboratory University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
  • Mende K; San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Enniss B; San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA.
  • Feig J; Bexar County Medical Examiner's Office, San Antonio, Texas, USA.
  • Ganesan A; Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
  • Rini EA; Landstuhl Regional Medical Center, Landstuhl, Germany.
  • Vento TJ; San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA.
J Clin Microbiol ; 53(6): 1968-75, 2015 Jun.
Article en En | MEDLINE | ID: mdl-25832301
ABSTRACT
We describe a 22-year-old soldier with 19% total body surface area burns, polytrauma, and sequence- and culture-confirmed Pythium aphanidermatum wound infection. Antemortem histopathology suggested disseminated Pythium infection, including brain involvement; however, postmortem PCR revealed Cunninghamella elegans, Lichtheimia corymbifera, and Saksenaea vasiformis coinfection. The utility of molecular diagnostics in invasive fungal infections is discussed.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pythium / Infección de Heridas / Traumatismos por Explosión / Pitiosis / Personal Militar Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: J Clin Microbiol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pythium / Infección de Heridas / Traumatismos por Explosión / Pitiosis / Personal Militar Tipo de estudio: Diagnostic_studies Límite: Adult / Humans / Male Idioma: En Revista: J Clin Microbiol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos