Lysophosphatidic acid signalling in development.
Development
; 142(8): 1390-5, 2015 Apr 15.
Article
en En
| MEDLINE
| ID: mdl-25852197
Lysophosphatidic acid (LPA) is a bioactive phospholipid that is present in all tissues examined to date. LPA signals extracellularly via cognate G protein-coupled receptors to mediate cellular processes such as survival, proliferation, differentiation, migration, adhesion and morphology. These LPA-influenced processes impact many aspects of organismal development. In particular, LPA signalling has been shown to affect fertility and reproduction, formation of the nervous system, and development of the vasculature. Here and in the accompanying poster, we review the developmentally related features of LPA signalling.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Lisofosfolípidos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Development
Asunto de la revista:
BIOLOGIA
/
EMBRIOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos