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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Lu, Xiaoming; Zoller, Erin E; Weirauch, Matthew T; Wu, Zhiguo; Namjou, Bahram; Williams, Adrienne H; Ziegler, Julie T; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Adler, Adam; Shen, Nan; Nath, Swapan K; Stevens, Anne M; Freedman, Barry I; Tsao, Betty P; Jacob, Chaim O; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; Anaya, Juan-Manuel; James, Judith A; Sivils, Kathy L; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Joo, Young Bin; Choi, Jeongim; Bae, Sang-Cheol; Boackle, Susan A; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Greis, Kenneth D; Kaufman, Kenneth M; Harley, John B; Kottyan, Leah C.
Afiliación
  • Lu X; Immunology Graduate Program, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Zoller EE; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Weirauch MT; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Wu Z; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Namjou B; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Williams AH; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Ziegler JT; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Comeau ME; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Marion MC; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Glenn SB; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Adler A; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Shen N; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Joint Molecular Rheumatology Laboratory, Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine in collaboration with Shanghai In
  • Nath SK; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Stevens AM; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101, USA; Division of Rheumatology, Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
  • Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Tsao BP; Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Jacob CO; Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
  • Kamen DL; Division of Rheumatology, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Brown EE; Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Gilkeson GS; Division of Rheumatology, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Alarcón GS; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Reveille JD; Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Anaya JM; Center for Autoimmune Diseases Research, Universidad del Rosario, 110010 Bogota, Colombia.
  • James JA; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  • Sivils KL; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Criswell LA; Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94117, USA.
  • Vilá LM; Division of Rheumatology, Department of Medicine, School of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA.
  • Alarcón-Riquelme ME; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Center for Genomics and Oncological Research, Pfizer-University of Granada-Junta de Andalucia, Granada 18016, Spain.
  • Petri M; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.
  • Scofield RH; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK 73104, USA.
  • Kimberly RP; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Ramsey-Goldman R; Division of Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Joo YB; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-792, Korea.
  • Choi J; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-792, Korea.
  • Bae SC; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul 133-792, Korea.
  • Boackle SA; Division of Rheumatology, School of Medicine, University of Colorado, Aurora, CO 80045, USA.
  • Graham DC; Divisions of Genetics and Molecular Medicine and Immunology, King's College London, Strand, London WC2R 2LS, UK.
  • Vyse TJ; Divisions of Genetics and Molecular Medicine and Immunology, King's College London, Strand, London WC2R 2LS, UK.
  • Guthridge JM; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Gaffney PM; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Langefeld CD; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
  • Kelly JA; Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.
  • Greis KD; Cancer Biology, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA.
  • Kaufman KM; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.
  • Harley JB; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.
  • Kottyan LC; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA. Electronic address: leah.kottyan@cchmc.org.
Am J Hum Genet ; 96(5): 731-9, 2015 May 07.
Article en En | MEDLINE | ID: mdl-25865496
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Factor de Transcripción STAT1 / Proteína Proto-Oncogénica c-ets-1 / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Factor de Transcripción STAT1 / Proteína Proto-Oncogénica c-ets-1 / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos