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Discovery of a novel Kv7 channel opener as a treatment for epilepsy.
Davoren, Jennifer E; Claffey, Michelle M; Snow, Sheri L; Reese, Matthew R; Arora, Gaurav; Butler, Christopher R; Boscoe, Brian P; Chenard, Lois; DeNinno, Shari L; Drozda, Susan E; Duplantier, Allen J; Moine, Ludivine; Rogers, Bruce N; Rong, SuoBao; Schuyten, Katherine; Wright, Ann S; Zhang, Lei; Serpa, Kevin A; Weber, Mark L; Stolyar, Polina; Whisman, Tammy L; Baker, Karen; Tse, Karen; Clark, Alan J; Rong, Haojing; Mather, Robert J; Lowe, John A.
Afiliación
  • Davoren JE; Pfizer, 610 Main Street, Cambridge, MA, United States.
  • Claffey MM; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Snow SL; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Reese MR; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Arora G; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Butler CR; Pfizer, 610 Main Street, Cambridge, MA, United States.
  • Boscoe BP; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Chenard L; Pfizer, Eastern Point Road, Groton, CT, United States.
  • DeNinno SL; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Drozda SE; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Duplantier AJ; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Moine L; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Rogers BN; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Rong S; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Schuyten K; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Wright AS; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Zhang L; Pfizer, 610 Main Street, Cambridge, MA, United States.
  • Serpa KA; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Weber ML; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Stolyar P; Pfizer, 610 Main Street, Cambridge, MA, United States.
  • Whisman TL; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Baker K; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Tse K; Pfizer, Drug Safety Research & Development, Sandwich, United Kingdom.
  • Clark AJ; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Rong H; Pfizer, Eastern Point Road, Groton, CT, United States.
  • Mather RJ; AstraZeneca Neuroscience iMED, 141 Portland St., Cambridge, MA, United States.
  • Lowe JA; JL3Pharma LLC, 28 Cove Side Lane, Stonington, CT, United States. Electronic address: jal3rd@gmail.com.
Bioorg Med Chem Lett ; 25(21): 4941-4944, 2015 Nov 01.
Article en En | MEDLINE | ID: mdl-25987375
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Pirimidinas / Activación del Canal Iónico / Epilepsia / Canal de Potasio KCNQ2 / Descubrimiento de Drogas Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Pirimidinas / Activación del Canal Iónico / Epilepsia / Canal de Potasio KCNQ2 / Descubrimiento de Drogas Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos