Vaccine associated paralytic poliomyelitis cases from children presenting with acute flaccid paralysis in Uganda.
J Med Virol
; 87(12): 2163-7, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26058454
ABSTRACT
A retrospective study to identify VAPP cases from the entire Uganda was conducted between January 2003 and December 2011. Eleven of the 106 AFP cases were VAPPs. The VAPP rate ranged from 0 to 3.39 cases per 1,000,000 birth cohorts and the peak was in 2009 when there was scaling up of OPV immunization activities following an importation of wild poliovirus in the country. All the subsequent polio suspect cases since then have been vaccine-associated polio cases. Our data support the strategy to withdraw OPV and introduce IPV progressively in order to mitigate against the paralysis arising from Sabin polioviruses.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Poliomielitis
/
Vacuna Antipolio Oral
/
Poliovirus
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
País/Región como asunto:
Africa
Idioma:
En
Revista:
J Med Virol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Uganda