Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFß1.

Sosulski, Meredith L; Gongora, Rafael; Danchuk, Svitlana; Dong, Chunmin; Luo, Fayong; Sanchez, Cecilia G

Sosulski, Meredith L; Gongora, Rafael; Danchuk, Svitlana; Dong, Chunmin; Luo, Fayong; Sanchez, Cecilia G.

Afiliación

Sosulski ML; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Gongora R; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Danchuk S; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Dong C; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Luo F; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.
Sanchez CG; Department of Medicine, Division of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA, 70112, USA.

Aging Cell ; 14(5): 774-83, 2015 Oct.

Article en En | MEDLINE | ID: mdl-26059457

Asunto(s)

Envejecimiento; Autofagia; Fibrosis Pulmonar/metabolismo; Fibrosis Pulmonar/patología; Factor de Crecimiento Transformador beta1/metabolismo; Animales; Diferenciación Celular; Células Cultivadas; Fibroblastos/citología; Fibroblastos/metabolismo; Humanos; Pulmón/citología; Pulmón/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Mitocondrias/metabolismo; Estrés Oxidativo; Fibrosis Pulmonar/genética; Especies Reactivas de Oxígeno/metabolismo; Factor de Crecimiento Transformador beta1/genética

Palabras clave

PINK1; TGFß1; aging; autophagy; lung fibrosis; lung injury; mitophagy; resveratrol

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fibrosis Pulmonar / Autofagia / Envejecimiento / Factor de Crecimiento Transformador beta1 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Aging Cell Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

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