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Biased Gs versus Gq proteins and ß-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond network.
Valentin-Hansen, Louise; Frimurer, Thomas M; Mokrosinski, Jacek; Holliday, Nicholas D; Schwartz, Thue W.
Afiliación
  • Valentin-Hansen L; From the Laboratory for Molecular Pharmacology, Department of Neuroscience and Pharmacology, The Panum Institute, Novo Nordisk Foundation Center for Basic Metabolic Research, and.
  • Frimurer TM; Novo Nordisk Foundation Center for Protein Research,University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark and.
  • Mokrosinski J; From the Laboratory for Molecular Pharmacology, Department of Neuroscience and Pharmacology, The Panum Institute, Novo Nordisk Foundation Center for Basic Metabolic Research, and.
  • Holliday ND; the Cell Signaling Research Group, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
  • Schwartz TW; From the Laboratory for Molecular Pharmacology, Department of Neuroscience and Pharmacology, The Panum Institute, Novo Nordisk Foundation Center for Basic Metabolic Research, and tws@sund.ku.dk.
J Biol Chem ; 290(40): 24495-508, 2015 Oct 02.
Article en En | MEDLINE | ID: mdl-26269596
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores de Neuroquinina-1 / Subunidades alfa de la Proteína de Unión al GTP Gs / Arrestinas / Subunidades alfa de la Proteína de Unión al GTP Gq-G11 / Receptores Acoplados a Proteínas G Tipo de estudio: Health_economic_evaluation Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores de Neuroquinina-1 / Subunidades alfa de la Proteína de Unión al GTP Gs / Arrestinas / Subunidades alfa de la Proteína de Unión al GTP Gq-G11 / Receptores Acoplados a Proteínas G Tipo de estudio: Health_economic_evaluation Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article