Stroke: advances in medical therapy and acute stroke intervention.
Curr Cardiol Rep
; 17(10): 79, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-26277364
ABSTRACT
Evidence-based therapeutic options for stroke continue to emerge based on results from well-designed clinical studies. Ischemic stroke far exceeds hemorrhagic stroke in terms of prevalence and incidence, both in the USA and worldwide. The public health effect of reducing death and disability related to ischemic stroke justifies the resources that have been invested in identifying safe and effective treatments. The emergence of novel oral anticoagulants for ischemic stroke prevention in atrial fibrillation has introduced complexity to clinical decision making for patients with this common cardiac arrhythmia. Some accepted ischemic stroke preventative strategies, such as carotid revascularization for asymptomatic carotid stenosis, require reassessment, given advances in risk factor management, antithrombotic therapy, and surgical techniques. Intra-arterial therapy, particularly with stent retrievers after intravenous tissue plasminogen activator, has recently been demonstrated to improve functional outcomes and will require investment in system-based care models to ensure that effective treatments are received by patients in a timely fashion. The purpose of this review is to describe recent advances in medical and surgical approaches to ischemic stroke prevention and acute treatment. Results from recently published clinical trials will be highlighted along with ongoing clinical trials addressing key questions in ischemic stroke management and prevention where equipoise remains.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Prevención Primaria
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Fibrilación Atrial
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Vigilancia de la Población
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Salud Pública
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Accidente Cerebrovascular
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Anticoagulantes
Tipo de estudio:
Etiology_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Cardiol Rep
Asunto de la revista:
CARDIOLOGIA
Año:
2015
Tipo del documento:
Article