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Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration.
Singh, Ruchira; Kuai, David; Guziewicz, Karina E; Meyer, Jackelyn; Wilson, Molly; Lu, Jianfeng; Smith, Molly; Clark, Eric; Verhoeven, Amelia; Aguirre, Gustavo D; Gamm, David M.
Afiliación
  • Singh R; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA; McPherson Eye Research Institute, University of Wisconsin, Madison, Wisconsin, USA.
  • Kuai D; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Guziewicz KE; Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Meyer J; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Wilson M; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Lu J; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Smith M; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Clark E; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Verhoeven A; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Aguirre GD; Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Gamm DM; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA; McPherson Eye Research Institute, University of Wisconsin, Madison, Wisconsin, USA; Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA. Electronic address: dgamm@wisc.edu.
Mol Ther ; 23(11): 1700-1711, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26300224
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácido Valproico / Sirolimus / Inhibidores Enzimáticos / Segmento Externo de las Células Fotorreceptoras Retinianas / Epitelio Pigmentado de la Retina / Células Madre Pluripotentes Inducidas / Distrofia Macular Viteliforme / Proteolisis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácido Valproico / Sirolimus / Inhibidores Enzimáticos / Segmento Externo de las Células Fotorreceptoras Retinianas / Epitelio Pigmentado de la Retina / Células Madre Pluripotentes Inducidas / Distrofia Macular Viteliforme / Proteolisis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos