ATRX loss in adult supratentorial diffuse astrocytomas correlates with p53 over expression and IDH1 mutation and predicts better outcome in p53 accumulated patients.

Shao, Li-Wei; Pan, Yi; Qi, Xue-Ling; Li, Yong-Xiao; Ma, Xiao-Long; Yi, Wei-Ning; Zhang, Jing; Zhong, Yan-Feng; Chang, Qing

Shao, Li-Wei; Pan, Yi; Qi, Xue-Ling; Li, Yong-Xiao; Ma, Xiao-Long; Yi, Wei-Ning; Zhang, Jing; Zhong, Yan-Feng; Chang, Qing.

Afiliación

Shao LW; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China.
Pan Y; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China.
Qi XL; Department of Pathology, Beijing Sanbo Brain Hospital, Beijing, China.
Li YX; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China.
Ma XL; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China.
Yi WN; Department of Epidemiology and Health Statistics, Peking University, Beijing, China.
Zhang J; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China and Department of Neuropathology, Harborview Medical Center, University of Washington School of Medicine, Seattle, WA, USA.
Zhong YF; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing, China.
Chang Q; Department of Pathology, School of Basic Medical Science, Peking University Third Hospital, Peking University, Beijing. China qingchang@bjmu.edu.cn.

Histol Histopathol ; 31(1): 103-14, 2016 Jan.

Article en En | MEDLINE | ID: mdl-26395639

Asunto(s)

Astrocitoma/genética; ADN Helicasas/genética; Isocitrato Deshidrogenasa/genética; Proteínas Nucleares/genética; Neoplasias Supratentoriales/genética; Proteína p53 Supresora de Tumor/genética; Adulto; Anciano; Anciano de 80 o más Años; Pueblo Asiatico; Metilasas de Modificación del ADN/genética; Enzimas Reparadoras del ADN/genética; Femenino; Eliminación de Gen; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Masculino; Persona de Mediana Edad; Mutación/genética; Clasificación del Tumor; Análisis de Supervivencia; Resultado del Tratamiento; Proteínas Supresoras de Tumor/genética; Proteína Nuclear Ligada al Cromosoma X; Adulto Joven

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Astrocitoma / Proteínas Nucleares / Neoplasias Supratentoriales / Proteína p53 Supresora de Tumor / ADN Helicasas / Isocitrato Deshidrogenasa Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Histol Histopathol Asunto de la revista: HISTOLOGIA / PATOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China

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