Structures for G-Protein-Coupled Receptor Tetramers in Complex with G Proteins.
Trends Biochem Sci
; 40(10): 548-551, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-26410595
G-Protein-coupled receptors (GPCRs) were classically described as monomers. We now appreciate that they also function as homo- and hetero-oligomers, for which structural information is lacking. Here, we use available 3D structures and biochemical considerations to present and evaluate experimentally testable structural models for GPCR oligomers and associated G proteins.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Proteínas de Unión al GTP
/
Receptores Acoplados a Proteínas G
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Biochem Sci
Año:
2015
Tipo del documento:
Article
País de afiliación:
España