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Elucidation of DnaE as the Antibacterial Target of the Natural Product, Nargenicin.
Painter, Ronald E; Adam, Gregory C; Arocho, Marta; DiNunzio, Edward; Donald, Robert G K; Dorso, Karen; Genilloud, Olga; Gill, Charles; Goetz, Michael; Hairston, Nichelle N; Murgolo, Nicholas; Nare, Bakela; Olsen, David B; Powles, Maryann; Racine, Fred; Su, Jing; Vicente, Francisca; Wisniewski, Douglas; Xiao, Li; Hammond, Milton; Young, Katherine.
Afiliación
  • Painter RE; In vitro Pharmacology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Adam GC; Screening and Protein Sciences, Merck Research Laboratories, North Wales, PA 19454, USA.
  • Arocho M; Medicinal Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • DiNunzio E; In vitro Pharmacology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Donald RG; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Dorso K; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Genilloud O; Centro de Investigación Básica (CIBE), Merck Sharp & Dhome de España, S.A., 28027 Madrid, Spain.
  • Gill C; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Goetz M; Medicinal Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Hairston NN; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Murgolo N; Discovery Pharmacogenomics, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Nare B; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Olsen DB; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Powles M; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Racine F; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Su J; Medicinal Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Vicente F; Centro de Investigación Básica (CIBE), Merck Sharp & Dhome de España, S.A., 28027 Madrid, Spain.
  • Wisniewski D; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Xiao L; Medicinal Chemistry, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Hammond M; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA.
  • Young K; Infectious Disease Biology, Merck Research Laboratories, Kenilworth, NJ 07033, USA. Electronic address: katherine_young@merck.com.
Chem Biol ; 22(10): 1362-73, 2015 Oct 22.
Article en En | MEDLINE | ID: mdl-26456734

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN Polimerasa III / Descubrimiento de Drogas Idioma: En Revista: Chem Biol Asunto de la revista: BIOLOGIA / BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN Polimerasa III / Descubrimiento de Drogas Idioma: En Revista: Chem Biol Asunto de la revista: BIOLOGIA / BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos