Primary Prevention of Sudden Death in Patients With Valvular Cardiomyopathy.
Rev Esp Cardiol (Engl Ed)
; 69(3): 272-8, 2016 Mar.
Article
en En
| MEDLINE
| ID: mdl-26481284
ABSTRACT
INTRODUCTION AND OBJECTIVES:
Few data exist on the outcomes of valvular cardiomyopathy patients referred for defibrillator implantation for primary prevention. The aim of the present study was to describe the outcomes of this cardiomyopathy subgroup.METHODS:
This multicenter retrospective study included consecutive patients referred for defibrillator implantation to 15 Spanish centers in 2010 and 2011, and to 3 centers after 1 January 2008.RESULTS:
Of 1174 patients, 73 (6.2%) had valvular cardiomyopathy. These patients had worse functional class, wider QRS, and a history of atrial fibrillation vs patients with ischemic (n=659; 56.1%) or dilated (n=442; 37.6%) cardiomyopathy. During a follow-up of 38.1 ± 21.3 months, 197 patients (16.7%) died, without significant differences among the groups (19.2% in the valvular cardiomyopathy group, 15.8% in the ischemic cardiomyopathy group, and 17.9% in the dilated cardiomyopathy group; P=.2); 136 died of cardiovascular causes (11.6%), without significant differences among the groups (12.3%, 10.5%, and 13.1%, respectively; P=.1). Although there were no differences in the proportion of appropriate defibrillator interventions (13.7%, 17.9%, and 18.8%; P=.4), there was a difference in inappropriate interventions (8.2%, 7.1%, and 12.0%, respectively; P=.03).CONCLUSIONS:
All-cause and cardiovascular mortality in patients with valvular cardiomyopathy were similar to those in other patients referred for defibrillator implantation. They also had similar rates of appropriate interventions. These data suggest that defibrillator implantation in this patient group confers a similar benefit to that obtained by patients with ischemic or dilated cardiomyopathy.Palabras clave
Appropriate interventions; Desfibrilador automático implantable; Implantable cardioverter-defibrillator; Inappropriate interventions; Intervenciones apropiadas; Intervenciones inapropiadas; Miocardiopatía valvular; Prevención primaria de muerte súbita cardiaca; Primary prevention of sudden cardiac death; Valvular cardiomyopathy
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Cardiomiopatía Dilatada
/
Muerte Súbita Cardíaca
/
Isquemia Miocárdica
/
Enfermedades de las Válvulas Cardíacas
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Rev Esp Cardiol (Engl Ed)
Año:
2016
Tipo del documento:
Article