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Intravenous pegylated asparaginase versus intramuscular native Escherichia coli L-asparaginase in newly diagnosed childhood acute lymphoblastic leukaemia (DFCI 05-001): a randomised, open-label phase 3 trial.
Place, Andrew E; Stevenson, Kristen E; Vrooman, Lynda M; Harris, Marian H; Hunt, Sarah K; O'Brien, Jane E; Supko, Jeffrey G; Asselin, Barbara L; Athale, Uma H; Clavell, Luis A; Cole, Peter D; Kelly, Kara M; Laverdiere, Caroline; Leclerc, Jean-Marie; Michon, Bruno; Schorin, Marshall A; Welch, Jennifer J G; Lipshultz, Steven E; Kutok, Jeffery L; Blonquist, Traci M; Neuberg, Donna S; Sallan, Stephen E; Silverman, Lewis B.
Afiliación
  • Place AE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Stevenson KE; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Vrooman LM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Harris MH; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Hunt SK; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • O'Brien JE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Supko JG; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Asselin BL; Department of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, NY, USA.
  • Athale UH; Division of Pediatric Hematology/Oncology, McMaster University, Hamilton, ON, Canada.
  • Clavell LA; Division of Pediatric Oncology, San Jorge Children's Hospital, San Juan, Puerto Rico.
  • Cole PD; Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Kelly KM; Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Medical Center, New York-Presbyterian Morgan Stanley Children's Hospital New York, NY, USA.
  • Laverdiere C; Division of Hematology and Oncology, Hospital Sainte-Justine, University of Montreal, Montreal, Canada.
  • Leclerc JM; Division of Hematology and Oncology, Hospital Sainte-Justine, University of Montreal, Montreal, Canada.
  • Michon B; Division of Hematology-Oncology, Centre Hospitalier Universite de Quebec, Quebec City, Canada.
  • Schorin MA; Inova Fairfax Hospital for Children, Falls Church, VA, USA.
  • Welch JJ; Division of Pediatric Hematology-Oncology, Hasbro Children's Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Lipshultz SE; Department of Pediatrics, Wayne State University Medical School, Detroit, MI, USA.
  • Kutok JL; Infinity Pharmaceuticals, Cambridge, MA, USA.
  • Blonquist TM; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Neuberg DS; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Sallan SE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Silverman LB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: lewis_silverman@dfci.harvard.edu.
Lancet Oncol ; 16(16): 1677-90, 2015 Dec.
Article en En | MEDLINE | ID: mdl-26549586
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polietilenglicoles / Asparaginasa / Proteínas de Escherichia coli / Escherichia coli / Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polietilenglicoles / Asparaginasa / Proteínas de Escherichia coli / Escherichia coli / Leucemia-Linfoma Linfoblástico de Células Precursoras / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos