Role of Immune Therapies for Myeloma.
J Natl Compr Canc Netw
; 13(11): 1440-7, 2015 Nov.
Article
en En
| MEDLINE
| ID: mdl-26553769
ABSTRACT
Immune therapy has emerged as a promising area of cancer therapeutics based on its potential for tumor selectivity and targeting of chemotherapy-resistant clones. Allogeneic transplantation produces durable remissions in a subset of patients, albeit at the cost of graft- versus-host disease. Recent years have witnessed efforts to induce more selective immune responses via dendritic cell vaccines, autologous and engineered T-cell therapy, and immune checkpoint blockade. Optimizing these immunotherapeutic approaches, understanding how to best use them in combination, and determining how to integrate them with standard anti-myeloma therapy could provide the potential to alter the natural history of this disease.
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Bases de datos:
MEDLINE
Asunto principal:
Inmunoterapia
/
Mieloma Múltiple
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Natl Compr Canc Netw
Asunto de la revista:
NEOPLASIAS
Año:
2015
Tipo del documento:
Article