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Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.
Wu, Zining; Graybill, Todd L; Zeng, Xin; Platchek, Michael; Zhang, Jean; Bodmer, Vera Q; Wisnoski, David D; Deng, Jianghe; Coppo, Frank T; Yao, Gang; Tamburino, Alex; Scavello, Genaro; Franklin, G Joseph; Mataruse, Sibongile; Bedard, Katie L; Ding, Yun; Chai, Jing; Summerfield, Jennifer; Centrella, Paolo A; Messer, Jeffrey A; Pope, Andrew J; Israel, David I.
Afiliación
  • Wu Z; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Graybill TL; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Zeng X; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Platchek M; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Zhang J; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Bodmer VQ; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Wisnoski DD; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Deng J; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Coppo FT; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Yao G; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Tamburino A; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Scavello G; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Franklin GJ; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Mataruse S; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Bedard KL; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Ding Y; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Chai J; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Summerfield J; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Centrella PA; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Messer JA; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
  • Pope AJ; Molecular Discovery Research, GlaxoSmithKline , Collegeville, Pennsylvania 19426, United States.
  • Israel DI; Molecular Discovery Research, GlaxoSmithKline , Waltham, Massachusetts 02451, United States.
ACS Comb Sci ; 17(12): 722-31, 2015 Dec 14.
Article en En | MEDLINE | ID: mdl-26562224
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / ADN / Receptores de Neuroquinina-3 / Bibliotecas de Moléculas Pequeñas / Acetatos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: ACS Comb Sci Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quinolinas / ADN / Receptores de Neuroquinina-3 / Bibliotecas de Moléculas Pequeñas / Acetatos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: ACS Comb Sci Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos