Simultaneous Analysis of SEPT9 Promoter Methylation Status, Micronuclei Frequency, and Folate-Related Gene Polymorphisms: The Potential for a Novel Blood-Based Colorectal Cancer Biomarker.

Ravegnini, Gloria; Zolezzi Moraga, Juan Manuel; Maffei, Francesca; Musti, Muriel; Zenesini, Corrado; Simeon, Vittorio; Sammarini, Giulia; Festi, Davide; Hrelia, Patrizia; Angelini, Sabrina

Ravegnini, Gloria; Zolezzi Moraga, Juan Manuel; Maffei, Francesca; Musti, Muriel; Zenesini, Corrado; Simeon, Vittorio; Sammarini, Giulia; Festi, Davide; Hrelia, Patrizia; Angelini, Sabrina.

Afiliación

Ravegnini G; Department of Pharmacy and Biotechnology, University of Bologna, via Irnerio 48, 40126 Bologna, Italy. gloria.ravegnini2@unibo.it.
Zolezzi Moraga JM; Department of Pharmacy and Biotechnology, University of Bologna, via Irnerio 48, 40126 Bologna, Italy. juan.zolezzimoraga@gmail.com.
Maffei F; Laboratorio de Biología Celular y Molecular, Departamento de Biología, Facultad de Ciencias, Universidad de Tarapacá, Arica 1000007, Chile. juan.zolezzimoraga@gmail.com.
Musti M; Department for Life Quality Studies, University of Bologna, Corso d'Augusto 237, 47921 Rimini, Italy. francesca.maffei@unibo.it.
Zenesini C; Unit of Epidemiology, Health Promotion and Risk Communication, Department of Public Health, Bologna Local Health Authority, Via del Seminario1, 40068 San lazzaro di Savena, Italy. m.musti@ausl.bologna.it.
Simeon V; Unit of Epidemiology and Biostatistics, IRCCS, ISNB, Via Altura 3, 40139 Bologna, Italy. zenesinicorrado@gmail.com.
Sammarini G; Laboratory of Pre-Clinical and Translational Research Reference Cancer Center of Basilicata, Scientific Institute of Hospitalization and Treatment, Rionero in Vulture, 85028 Potenza, Italy. vittorio.simeon@crob.it.
Festi D; Department of Pharmacy and Biotechnology, University of Bologna, via Irnerio 48, 40126 Bologna, Italy. giulia.sammarini2@unibo.it.
Hrelia P; Department of Clinical Medicine, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. davide.festi@unibo.it.
Angelini S; Department of Pharmacy and Biotechnology, University of Bologna, via Irnerio 48, 40126 Bologna, Italy. patriza.hrelia@unibo.it.

Int J Mol Sci ; 16(12): 28486-97, 2015 Dec 01.

Article en En | MEDLINE | ID: mdl-26633373

Asunto(s)

Neoplasias Colorrectales/diagnóstico; Neoplasias Colorrectales/genética; Metilación de ADN; Micronúcleos con Defecto Cromosómico; Polimorfismo de Nucleótido Simple; Regiones Promotoras Genéticas; Septinas/genética; Poliposis Adenomatosa del Colon/diagnóstico; Poliposis Adenomatosa del Colon/genética; Poliposis Adenomatosa del Colon/metabolismo; Anciano; Anciano de 80 o más Años; Alelos; Biomarcadores de Tumor; Estudios de Casos y Controles; Línea Celular Tumoral; Neoplasias Colorrectales/metabolismo; Femenino; Ácido Fólico/metabolismo; Frecuencia de los Genes; Genotipo; Humanos; Mutación INDEL; Masculino; Persona de Mediana Edad; Oportunidad Relativa; Curva ROC

Palabras clave

SEPT9 methylation; colorectal cancer; genetic polymorphisms; micronuclei

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Regiones Promotoras Genéticas / Metilación de ADN / Polimorfismo de Nucleótido Simple / Micronúcleos con Defecto Cromosómico / Septinas Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Mol Sci Año: 2015 Tipo del documento: Article País de afiliación: Italia

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