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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-ß-D-ribose 2'-oxidase.
Landge, Sudhir; Mullick, Amrita B; Nagalapur, Kavitha; Neres, João; Subbulakshmi, Venkita; Murugan, Kannan; Ghosh, Anirban; Sadler, Claire; Fellows, Mick D; Humnabadkar, Vaishali; Mahadevaswamy, Jyothi; Vachaspati, Prakash; Sharma, Sreevalli; Kaur, Parvinder; Mallya, Meenakshi; Rudrapatna, Suresh; Awasthy, Disha; Sambandamurthy, Vasan K; Pojer, Florence; Cole, Stewart T; Balganesh, Tanjore S; Ugarkar, Bheemarao G; Balasubramanian, V; Bandodkar, Balachandra S; Panda, Manoranjan; Ramachandran, Vasanthi.
Afiliación
  • Landge S; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Mullick AB; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Nagalapur K; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Neres J; École Polytechnique Fédérale de Lausanne, Global Health Institute, Switzerland.
  • Subbulakshmi V; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Murugan K; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Ghosh A; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Sadler C; Global Safety Assessment, AstraZeneca, Alderley Park, Mereside, UK.
  • Fellows MD; Global Safety Assessment, AstraZeneca, Alderley Park, Mereside, UK.
  • Humnabadkar V; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Mahadevaswamy J; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Vachaspati P; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Sharma S; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Kaur P; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Mallya M; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Rudrapatna S; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Awasthy D; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Sambandamurthy VK; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Pojer F; École Polytechnique Fédérale de Lausanne, Global Health Institute, Switzerland.
  • Cole ST; École Polytechnique Fédérale de Lausanne, Global Health Institute, Switzerland.
  • Balganesh TS; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Ugarkar BG; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Balasubramanian V; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Bandodkar BS; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Panda M; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India.
  • Ramachandran V; iMed Infection, AstraZeneca India Pvt Ltd, Bangalore, India. Electronic address: vasanthi_epr@yahoo.com.
Bioorg Med Chem ; 23(24): 7694-710, 2015 Dec 15.
Article en En | MEDLINE | ID: mdl-26643218

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Oxidorreductasas de Alcohol / Benzotiazoles / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Oxidorreductasas de Alcohol / Benzotiazoles / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: India