Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice.

Kiraly, Alex J; Soliman, Eman; Jenkins, Audrey; Van Dross, Rukiyah T

Kiraly, Alex J; Soliman, Eman; Jenkins, Audrey; Van Dross, Rukiyah T.

Afiliación

Kiraly AJ; Department of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
Soliman E; Department of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
Jenkins A; Department of Comparative Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
Van Dross RT; Department of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC, USA. Electronic address: vandrossr@ecu.edu.

Prostaglandins Leukot Essent Fatty Acids ; 104: 44-53, 2016 Jan.

Article en En | MEDLINE | ID: mdl-26802941

Asunto(s)

Apigenina/uso terapéutico; Ciclooxigenasa 2/metabolismo; Dinoprostona/metabolismo; Epidermis/efectos de los fármacos; Epidermis/metabolismo; Subtipo EP1 de Receptores de Prostaglandina E/metabolismo; Animales; Diferenciación Celular/efectos de los fármacos; Femenino; Ratones; Neoplasias Cutáneas/tratamiento farmacológico

Palabras clave

Apigenin; COX-2; Differentiation; EP1; Proliferation; Skin cancer

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Apigenina / Epidermis / Ciclooxigenasa 2 / Subtipo EP1 de Receptores de Prostaglandina E Límite: Animals Idioma: En Revista: Prostaglandins Leukot Essent Fatty Acids Asunto de la revista: ENDOCRINOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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